Gene description for Prkg1
Gene name	protein kinase, cGMP-dependent, type I
Gene symbol	Prkg1
Other names/aliases	AW125416 CGKI Gm19690 Prkg1b Prkgr1b
Species	Mus musculus
Database cross references - Prkg1
ExoCarta	ExoCarta_19091
Vesiclepedia	VP_19091
Entrez Gene	19091
UniProt	P0C605
Prkg1 identified in sEVs derived from the following tissue/cell type
Mast cells	17486113

Gene ontology annotations for Prkg1

Molecular Function     protein kinase activity GO:0004672 IDA     protein kinase activity GO:0004672 ISO     cGMP-dependent protein kinase activity GO:0004692 IDA     cGMP-dependent protein kinase activity GO:0004692 ISO     calcium channel regulator activity GO:0005246 ISO     calcium channel regulator activity GO:0005246 ISS     protein binding GO:0005515 IPI     ATP binding GO:0005524 IEA     cGMP binding GO:0030553 IDA     identical protein binding GO:0042802 IEA     identical protein binding GO:0042802 ISO     mitogen-activated protein kinase p38 binding GO:0048273 IEA     protein serine kinase activity GO:0106310 IEA Biological Process     neuron migration GO:0001764 IMP     protein phosphorylation GO:0006468 IDA     signal transduction GO:0007165 IBA     signal transduction GO:0007165 IDA     positive regulation of cytosolic calcium ion concentration GO:0007204 IEA     spermatid development GO:0007286 IEA     negative regulation of inositol phosphate biosynthetic process GO:0010920 IEA     negative regulation of glutamate secretion GO:0014050 IEA     dendrite development GO:0016358 IMP     cGMP-mediated signaling GO:0019934 IMP     cerebellum development GO:0021549 IEA     forebrain development GO:0030900 IMP     positive regulation of circadian rhythm GO:0042753 IEA     regulation of GTPase activity GO:0043087 ISO     regulation of GTPase activity GO:0043087 ISS     negative regulation of smooth muscle contraction GO:0045986 IMP     collateral sprouting GO:0048668 IMP     relaxation of vascular associated smooth muscle GO:0060087 IMP     cell growth involved in cardiac muscle cell development GO:0061049 IEA     negative regulation of platelet aggregation GO:0090331 ISO     negative regulation of platelet aggregation GO:0090331 ISS     negative regulation of vascular associated smooth muscle cell proliferation GO:1904706 IEA     negative regulation of vascular associated smooth muscle cell proliferation GO:1904706 ISO     negative regulation of vascular associated smooth muscle cell migration GO:1904753 IEA     negative regulation of vascular associated smooth muscle cell migration GO:1904753 ISO     regulation of testosterone biosynthetic process GO:2000224 IEA Subcellular Localization     acrosomal vesicle GO:0001669 IEA     nucleoplasm GO:0005654 IEA     cytoplasm GO:0005737 ISO     cytoplasm GO:0005737 ISS     Golgi apparatus GO:0005794 IDA     plasma membrane GO:0005886 IDA     plasma membrane GO:0005886 IMP     plasma membrane GO:0005886 ISO     sarcolemma GO:0042383 IEA