Experiment description of studies that identified Notch2 in sEVs

1 Experiment ID 907 MISEV standards ✔ EM Biophysical techniques ✔ Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a Enriched markers ✔ HSPA5 Negative markers ✔ NTA Particle analysis Identified molecule Protein Identification method Mass spectrometry PubMed ID 37309723     Organism Mus musculus Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells Authors "Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S." Journal name Proteomics Publication year 2023 Sample Colon cancer cells Sample name C26 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectrometry

2 Experiment ID 908 MISEV standards ✔ EM Biophysical techniques ✔ Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a Enriched markers ✔ HSPA5 Negative markers ✔ NTA Particle analysis Identified molecule Protein Identification method Mass spectrometry PubMed ID 37309723     Organism Mus musculus Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells Authors "Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S." Journal name Proteomics Publication year 2023 Sample T-cell lymphoma cells Sample name EL4 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectrometry

Protein-protein interactions for Notch2

Protein Interactor ExoCarta ID Identification method PubMed Species 1 Dtx4   Co-fractionation Mus musculus 2 Nphs2   Affinity Capture-MS Mus musculus 3 Jag1   Co-fractionation Mus musculus 4 Tmem173   Proximity Label-MS Mus musculus 5 Rbpj   Affinity Capture-Western Mus musculus 6 Psen1   Affinity Capture-Western Mus musculus 7 Umodl1   Co-fractionation Mus musculus 8 TRAF6 7189 Affinity Capture-Western Homo sapiens 9 Notch3   Co-fractionation Mus musculus 10 Rfng   Co-fractionation Mus musculus 11 Notch4   Co-fractionation Mus musculus 12 Egfl7   Affinity Capture-Western Mus musculus 13 EGFL7 51162 Affinity Capture-Western Homo sapiens 14 Psen2   Affinity Capture-Western Mus musculus 15 Jag2   Co-fractionation Mus musculus 16 MAP3K7   Affinity Capture-Western Homo sapiens View the network

Pathways in which Notch2 is involved

No pathways found