Gene description for Ndrg1
Gene name
N-myc downstream regulated gene 1
Gene symbol
Ndrg1
Other names/aliases
CAP43 CMT4D DRG1 HMSNL NMSL Ndr1 Ndrl PROXY1 RTP TDD5
Species
Mus musculus
Database cross references - Ndrg1
ExoCarta
ExoCarta_17988
Vesiclepedia
VP_17988
Entrez Gene
17988
UniProt
Q62433
Ndrg1 identified in sEVs derived from the following tissue/cell type
Colon cancer cells
37309723
T-cell lymphoma cells
37309723
Gene ontology annotations for Ndrg1
Experiment description of studies that identified Ndrg1 in sEVs
1
Experiment ID
907
MISEV standards
✔
EM
Biophysical techniques
✔
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
Enriched markers
✔
HSPA5
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
37309723
Organism
Mus musculus
Experiment description
Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors
"Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S."
Journal name
Proteomics
Publication year
2023
Sample
Colon cancer cells
Sample name
C26
Isolation/purification methods
Differential centrifugation Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry
2
Experiment ID
908
MISEV standards
✔
EM
Biophysical techniques
✔
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
Enriched markers
✔
HSPA5
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
37309723
Organism
Mus musculus
Experiment description
Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors
"Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S."
Journal name
Proteomics
Publication year
2023
Sample
T-cell lymphoma cells
Sample name
EL4
Isolation/purification methods
Differential centrifugation Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry
Protein-protein interactions for Ndrg1
Protein Interactor
ExoCarta ID
Identification method
PubMed
Species
1
Zer1
Co-fractionation
Mus musculus
2
Lnx1
Affinity Capture-MS
Mus musculus
3
Sstr3
Proximity Label-MS
Mus musculus
4
Upf1
19704
Co-fractionation
Mus musculus
5
Ruvbl2
20174
Co-fractionation
Mus musculus
6
Map2k6
Co-fractionation
Mus musculus
7
Tmsb4x
Co-fractionation
Mus musculus
8
Tprgl
Co-fractionation
Mus musculus
9
Nt5c3b
Co-fractionation
Mus musculus
10
Ptgds
Co-fractionation
Mus musculus
11
Kcnma1
Affinity Capture-MS
Mus musculus
View the network
image/svg+xml
Pathways in which Ndrg1 is involved
No pathways found