Gene description for Cdc25c
Gene name cell division cycle 25C
Gene symbol Cdc25c
Other names/aliases Cdc25
Species Mus musculus
 Database cross references - Cdc25c
ExoCarta ExoCarta_12532
Vesiclepedia VP_12532
Entrez Gene 12532
UniProt P48967  
 Cdc25c identified in sEVs derived from the following tissue/cell type
Mast cells 11145662    
 Gene ontology annotations for Cdc25c
Molecular Function
    protein tyrosine phosphatase activity GO:0004725 IBA
    non-membrane spanning protein tyrosine phosphatase activity GO:0004726 IEA
    protein binding GO:0005515 IPI
    protein kinase binding GO:0019901 IEA
    protein kinase binding GO:0019901 ISO
    protein tyrosine phosphatase activity, metal-dependent GO:0030946 IEA
    WW domain binding GO:0050699 IEA
    WW domain binding GO:0050699 ISO
    histone H2AXY142 phosphatase activity GO:0140793 IEA
Biological Process
    G2/M transition of mitotic cell cycle GO:0000086 IBA
    G2/M transition of mitotic cell cycle GO:0000086 IEA
    G2/M transition of mitotic cell cycle GO:0000086 ISO
    chromatin remodeling GO:0006338 IEA
    spermatogenesis GO:0007283 IEA
    positive regulation of G2/M transition of mitotic cell cycle GO:0010971 IBA
    cell division GO:0051301 IEA
    positive regulation of G2/MI transition of meiotic cell cycle GO:0110032 IBA
    positive regulation of cell cycle G2/M phase transition GO:1902751 IEA
Subcellular Localization
    nucleus GO:0005634 IBA
    nucleus GO:0005634 IDA
    nucleus GO:0005634 ISO
    cytoplasm GO:0005737 IBA
    cytoplasm GO:0005737 IDA
    mitochondrial intermembrane space GO:0005758 IDA
    perinuclear region of cytoplasm GO:0048471 IEA
    perinuclear region of cytoplasm GO:0048471 ISO
 Experiment description of studies that identified Cdc25c in sEVs
1
Experiment ID 5
MISEV standards
EM|IEM
Biophysical techniques
CD86|CD80
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 11145662    
Organism Mus musculus
Experiment description Mast cell-dependent B and T lymphocyte activation is mediated by the secretion of immunologically active exosomes.
Authors "Skokos D, Le Panse S, Villa I, Rousselle JC, Peronet R, David B, Namane A, Mecheri S"
Journal name JIMMU
Publication year 2001
Sample Mast cells
Sample name P815
MC9
Bone marrow-derived mast cells
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [MALDI TOF]
ELISA
 Protein-protein interactions for Cdc25c
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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