Gene description for PSMB11
Gene name proteasome (prosome, macropain) subunit, beta type, 11
Gene symbol PSMB11
Other names/aliases BETA5T
Species Homo sapiens
 Database cross references - PSMB11
ExoCarta ExoCarta_122706
Vesiclepedia VP_122706
Entrez Gene 122706
HGNC 31963
MIM 611137
UniProt A5LHX3  
 PSMB11 identified in sEVs derived from the following tissue/cell type
Thymus 23844026    
 Gene ontology annotations for PSMB11
Molecular Function
    endopeptidase activity GO:0004175 IBA
    threonine-type endopeptidase activity GO:0004298 IEA
    protein binding GO:0005515 IPI
    peptidase activity GO:0008233 IDA
Biological Process
    proteolysis GO:0006508 IDA
    T cell differentiation in thymus GO:0033077 IEA
    proteasome-mediated ubiquitin-dependent protein catabolic process GO:0043161 IBA
    CD8-positive, alpha-beta T cell differentiation GO:0043374 IEA
Subcellular Localization
    nucleus GO:0005634 IBA
    cytosol GO:0005829 IBA
    cytosol GO:0005829 TAS
    proteasome core complex, beta-subunit complex GO:0019774 IBA
    proteasome core complex, beta-subunit complex GO:0019774 ISS
 Experiment description of studies that identified PSMB11 in sEVs
1
Experiment ID 217
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|CD81|CD9|CD63
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors "Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O."
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for PSMB11
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 TLX3  
Two-hybrid Homo sapiens
2 PROP1  
Two-hybrid Homo sapiens
3 ILF3 3609
Affinity Capture-RNA Homo sapiens
4 HGS 9146
Two-hybrid Homo sapiens
View the network image/svg+xml



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