Gene description for Abcc5
Gene name	ATP-binding cassette, subfamily C (CFTR/MRP), member 5
Gene symbol	Abcc5
Other names/aliases	Abcc5a Mrp5
Species	Rattus norvegicus
Database cross references - Abcc5
ExoCarta	ExoCarta_116721
Vesiclepedia	VP_116721
Entrez Gene	116721
UniProt	Q9QYM0
Abcc5 identified in sEVs derived from the following tissue/cell type
Reticulocytes	21828046
Reticulocytes	21828046

Gene ontology annotations for Abcc5

Molecular Function     nucleotide binding GO:0000166 IEA     ATP binding GO:0005524 IEA     ABC-type xenobiotic transporter activity GO:0008559 IEA     ABC-type xenobiotic transporter activity GO:0008559 ISO     ABC-type xenobiotic transporter activity GO:0008559 ISS     purine nucleotide transmembrane transporter activity GO:0015216 IEA     purine nucleotide transmembrane transporter activity GO:0015216 ISO     heme transmembrane transporter activity GO:0015232 IEA     heme transmembrane transporter activity GO:0015232 ISO     heme transmembrane transporter activity GO:0015232 ISS     efflux transmembrane transporter activity GO:0015562 IEA     efflux transmembrane transporter activity GO:0015562 ISO     ATP hydrolysis activity GO:0016887 IEA     macromolecule transmembrane transporter activity GO:0022884 IEA     macromolecule transmembrane transporter activity GO:0022884 ISO     glutathione transmembrane transporter activity GO:0034634 IEA     glutathione transmembrane transporter activity GO:0034634 ISO     ATPase-coupled transmembrane transporter activity GO:0042626 IBA     ATPase-coupled transmembrane transporter activity GO:0042626 ISS     xenobiotic transmembrane transporter activity GO:0042910 ISO     ABC-type transporter activity GO:0140359 ISO     carbohydrate derivative transmembrane transporter activity GO:1901505 IEA     carbohydrate derivative transmembrane transporter activity GO:1901505 ISO Biological Process     purine nucleotide transport GO:0015865 ISO     hyaluronan biosynthetic process GO:0030213 IEA     hyaluronan biosynthetic process GO:0030213 ISO     response to lipopolysaccharide GO:0032496 IEP     response to insulin GO:0032868 IEP     glutathione transmembrane transport GO:0034775 IEA     glutathione transmembrane transport GO:0034775 ISO     heme transmembrane transport GO:0035351 IEA     heme transmembrane transport GO:0035351 ISO     heme transmembrane transport GO:0035351 ISS     xenobiotic transport GO:0042908 IEA     xenobiotic transport GO:0042908 ISO     transmembrane transport GO:0055085 IBA     cAMP transport GO:0070730 IEA     cAMP transport GO:0070730 ISO     cGMP transport GO:0070731 IEA     cGMP transport GO:0070731 ISO     folate transmembrane transport GO:0098838 IEA     folate transmembrane transport GO:0098838 ISO     folate transmembrane transport GO:0098838 ISS     export across plasma membrane GO:0140115 IEA     export across plasma membrane GO:0140115 ISO Subcellular Localization     Golgi lumen GO:0005796 IEA     plasma membrane GO:0005886 ISO     plasma membrane GO:0005886 ISO     endosome membrane GO:0010008 IEA     membrane GO:0016020 IBA     membrane GO:0016020 ISO     basolateral plasma membrane GO:0016323 IDA     basolateral plasma membrane GO:0016323 IEA     basolateral plasma membrane GO:0016323 ISO     apical plasma membrane GO:0016324 IEA     apical plasma membrane GO:0016324 ISO     apical plasma membrane GO:0016324 ISS     perinuclear region of cytoplasm GO:0048471 IDA